I am working on finalizing an electronic version of a large PDF file (600 page NIME proceedings), and have had some problems optimizing the PDF file. This may not be so strange, since the file is an assembly of 130 individual PDF files all made by different people and using all sorts of programs and OS. Usually, PDFCompress works wonders when it comes to reducing PDF file sizes, but for the proceedings-file it choked at some of the fonts.